Expression and localization of prohormone convertase 1/3 (SPC3) in porcine ovary.
نویسندگان
چکیده
Tissue distribution and cellular localization of PC1/3 mRNA in porcine tissues were examined by ribonuclease protection assay and in situ hybridization. PC1/3 mRNA was detected mainly in the corpus luteum of pregnant sow and brain. Within the ovary, PC1/3 and relaxin transcripts colocalized within large luteal cells. Levels of PC1/3 transcripts in corpora lutea increased as gestation advanced, parallel with an observed increase in relaxin transcripts. A role for PC1/3 in proprotein processing in the ovary is discussed.
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ورودعنوان ژورنال:
- Molecular reproduction and development
دوره 57 4 شماره
صفحات -
تاریخ انتشار 2000